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Claudine E. Bruck

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Prolifagen is a StartUp company located in Philadelphia and working on a local injectable medicine based on microRNA to regenerate heart muscle damaged by MI and prevent heart failure. [Approximately 400,000 people develop HF following massive MI yearly in US/EU combined, at a huge cost to society.]

We have shown regeneration of cardiac muscle in mice and have early data of regeneration in pigs. Our next milestone will be to define the extent of clinical benefit in a pig model of myocardial infarct, as a stepping stone to clinical trials.

We have issued patents in US/EU.

So far, our funding has been based on non-dilutive funding from founders and on a phase 1 SBIR grant. We are looking for strategic investment and/or collaboration/licensing.

Executive Summary